Surface Hydrophobic Modification of Fifth-Generation Hydroxyl-Terminated Poly(amidoamine) Dendrimers and Its Effect on Biocompatibility and Rheology

نویسندگان

  • Paul D. Hamilton
  • Donghui Z. Jacobs
  • Brian Rapp
  • Nathan Ravi
چکیده

H NMR spectra to support data for Table 1 and Figure 1: For synthesis of hydrophobically modified dendrimers, dodecyl chloroformate was adjusted to 5, 10 and 20 mol % of G5OH PAMAM dendrimer hydroxyl groups, and the amount of cholesteryl chloroformate was 0.86, 2, 5, and 20 mol % of dendrimer hydroxyl groups. The corresponding modified dendrimers were designated as D1, D2, D3 and C1, C2, C3, C4, respectively. H NMR spectra were recorded on a Varian Inova600MHz spectrometer in DMSO-d6 (Aldrich). VNMR software was used for integration values for structural analysis.

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عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2009